The identity of the person has not been released, and it is unclear how the body ended up in the water.
The Baltimore Firefighters IAFF Local 734 reported the incident on Thursday, after receiving reports of a body found in the Inner Harbor.
Crews were dispatched to the area of the 100 block of President, where they recovered the person’s body before 3 p.m.
SkyTeam 11 video showed numerous fire and police boats on the scene, as well as a large emergency response presence.
Police are urging drivers to expect traffic delays in the area as the investigation continues.
The discovery of the body is a tragic incident, and authorities are working to determine the circumstances surrounding the death.
Further information is expected to be released as the investigation progresses.